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Male mice with a mutation that prevented them producing any sperm have fathered offspring the natural way after a team in China fixed their infertility by CRISPR genome editing.
The technique could one day help many infertile men around the world. “I think this study is very exciting,” says Sarah Vij, a male infertility specialist at Cleveland Clinic Foundation in the US, who was not involved in the work. “Most of us think this is the future for these men.”
There are several known genetic mutations that prevent …