NCBI Bookshelf. The skeletal muscle relaxants Table are a heterogeneous group of medications acting both centrally and peripherally to relieve muscle spasms. These medications have been in wide use for decades and rarely cause liver disease. View in own window. Muscle relaxants are used to treat two different conditions: 1 spasticity from upper motor neuron syndromes as occurs in multiple sclerosis and 2 muscular pain or spasms from peripheral musculoskeletal diseases or injury such as low back pain. The muscle relaxants in current use have variable mechanisms of action, efficacy and adverse effects.
For your safety and appropriate treatment of your condition, always discuss any changes to your medications with your doctor beforehand. Some clinicians would agree that the medications in this class tend to be used more frequently than necessary, but clear data are lacking. Cyclobenzaprine and naproxen versus naproxen alone in the treatment of acute low back pain and muscle spasm. Featured Issue Featured Supplements. Muscle relaxants are thought to be useful in painful disorders based on the theory that pain induces spasm and spasm causes pain.
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